Ganoderic acid C2
Ganoderic acid C2
CAS: 103773-62-2
Molecular Formula: C30H46O7
Ganoderic acid C2 - Names and Identifiers
Ganoderic acid C2 - Physico-chemical Properties
| Molecular Formula | C30H46O7 |
| Molar Mass | 518.68 |
| Density | 1.22±0.1 g/cm3(Predicted) |
| Melting Point | 231～232℃ |
| Boling Point | 690.8±55.0 °C(Predicted) |
| Solubility | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Appearance | Powder |
| pKa | 4.78±0.23(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD04039842 |
Ganoderic acid C2 - Reference
| Reference Show more | 1. Fan Lei, Chen Qinming, Chen Zhang Jin, et al. Study on quality control method for multiple evaluation of Ganoderma lucidum [J]. China pharmacist, 2018, v.21(05):76-80. |
Ganoderic acid C2 - Reference Information
| Introduction | ganoderic acid C2 is a class of highly oxidized lanstane derivatives, which can effectively inhibit aldose reductase, and confirmed that its activity and its chemical structure in the free carboxyl group are closely related. There are three main analytical methods of ganoderic acid C2, such as high performance liquid chromatography, vanillin-perchloric acid colorimetric method and ultraviolet absorption method. |
| efficacy and function | Ganoderic acid C2 is a kind of triterpene with biological activity in Ganoderma lucidum, ganoderic acid C2 has potential anti-tumor biological activity, anti-histamine, anti-aging and cytotoxicity. Ganoderic acid C2 has a high inhibitory activity against rat lens aldose reduction (RLAR) with an IC50 value of 3.8 μm. |
| preparation of ganoderic acid C2 | the preparation method of ganoderic acid C2 is as follows:(1) weigh the raw material of ganoderma extract byproduct, add a certain amount of anhydrous ethanol, the ratio is 1:5, ultrasonic dissolution, after the solution is centrifuged, the supernatant is passed through 0.45 μm filter membrane, and the Ganoderma lucidum solution is obtained, which is used for pressing and standby;(2) flash medium pressure preparation of the collected liquid on the HPLC determination, respectively, to obtain the Ganoderma acid A, B, C2 mixture, water bath evaporation, for high pressure preparation;(3) Ganoderma acid A, B, after the C2 mixture is evaporated to dryness, it is dissolved by adding an appropriate amount of methanol, passed through the membrane, and the filtrate is prepared and purified by high pressure, and the collected liquid is prepared by Prep high pressure and determined by HPLC, and the Ganoderma acid monomer is obtained respectively, and then recrystallized, A pure ganoderic acid C2 was obtained. |
| Target | IC50: 3.8 µm (RLAR) |
| Storage Conditions | ganoderic acid C2 can be sealed at 2-8 ℃ and stored in the dark. |
Last Update：2024-04-09 20:45:29
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Product Name: Ganoderic Acid C2 Visit Supplier Webpage Request for quotationCAS: 103773-62-2
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Spot supply
Product Name: Ganoderic acid C2 Visit Supplier Webpage Request for quotationCAS: 103773-62-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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